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Image Search Results
Journal: Heliyon
Article Title: Triptolide attenuates cardiac remodeling by inhibiting pyroptosis and EndMT via modulating USP14/Keap1/Nrf2 pathway
doi: 10.1016/j.heliyon.2024.e24010
Figure Lengend Snippet: TP inhibits EndMT in cardiac remodeling models. (A – D) Western blot analysis of CD31, VE-Cadherin and α-SMA protein expression in mouse heart tissue (n = 6). (E – H) Western blot analysis of Slug, Snail and Twist protein expression in mouse heart tissue (n = 6). (I – L) Western blot analysis of CD31, VE-Cadherin and α-SMA in EN (HCAEC) (n = 6). (M – P) Western blot analysis of Slug, Snail and Twist in EN (HCAEC) (n = 6). All the values are presented as mean ± SD. # P < 0.05, ## P < 0.01 compared with Sham or Ctl group; *P < 0.05, **P < 0.01 compared with TAC or TGF-β1 group. The original blots were provided in supplementary data as .
Article Snippet: In our study,
Techniques: Western Blot, Expressing
Journal: Heliyon
Article Title: Triptolide attenuates cardiac remodeling by inhibiting pyroptosis and EndMT via modulating USP14/Keap1/Nrf2 pathway
doi: 10.1016/j.heliyon.2024.e24010
Figure Lengend Snippet: TP inhibits EndMT via Nrf2 pathway. (A – B) Western blot analysis of Nrf2 in EN (HCAEC) ( n = 6). (C – D) Western blot analysis of Nrf2 expression in the presence or absence of Nrf2 siRNA in EN (HCAEC) ( n = 6 ) . (E – H) CD31, VE-Cadherin and α-SMA expression elicited by TGF-β1 in the presence or absence of Nrf2 siRNA in EN (HCAEC) (n = 6) (I – L) Slug, Snail and Twist expression elicited by TGF-β1 in the presence or absence of Nrf2 siRNA in EN (HCAEC) (n = 6). All the values are presented as mean ± SD. # P < 0.05, ## P < 0.01 compared with Ctl group; *P < 0.05, **P < 0.01 compared with siRNA-NC group or TGF-β1 group; & P < 0.05, && P < 0.01 compared with TGF-β1+TP + scRNA group. The original blots were provided in supplementary data as .
Article Snippet: In our study,
Techniques: Western Blot, Expressing